PTN VIDEOS

The videos presented in this section require Windows Media Player which can be downloaded for free from the Microsoft Web site (Windows | Macintosh).

“Diagnosis and Treatment of Cervical Dystonia” by Joseph Jankovic

TCR (Start Time)	Topic
00:00:00:00	Sponsors and accreditation statement, faculty, CME advisor
00:02:36:00	Learning objectives
00:03:07:00 – 00:04:28:00	Disclosures
00:04:48:00	Definition, Prevalence, Epidemiology, and Diagnosis of CD
00:08:19:00	Clinical Features of CD
00:11:46:00	Treatment of CD
00:15:31:00	Evaluation of Patients With CD
00:17:14:00	Improving Response to Botulinum Toxin
00:18:10:00	Muscles Treated in CD According to Presentation
00:19:15:00	Efficacy of BoNT-A
00:23:05:00	Efficacy of BoNT-B
00:24:45:00	Immunogenicity
00:28:01:00	Factors That May Increase the Risk of Antibody Formation
00:30:04:00	Mechanism of Neutralizing Antibody Formation
00:31:42:00	Evidence-Based Outcomes and Long-Term Follow-up of Patients Treated With BoNT-A
00:35:35:00 – 00:36:30:00	Patient Case – BoNT-A For CD

“Molecular Basis for the Therapeutic Effectiveness of Botulinum Neurotoxins” by Oliver Dolly

TCR (Start Time)	Topic Discussed
00:37:26:00	Synaptic Transmission
00:39:00:00	Electron Tomography of Active Zones at Nerve Terminal
00:40:27:00	The Synaptic Vesicle
00:42:17:00	Botulinum Proteins
00:45:15:00	X-ray Crystallography of Botulinum Toxins
00:46:17:00	Targeting and Uptake of [125I]BoNT-A at Motor Nerve Terminals
00:48:30:00	Mechanism for the Inhibition of Neurotransmitter Release by BoNTs
00:50:48:00	Acknowledgements

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